Wuhan Nutra Biotechnology Co., Ltd.

Wuhan Nutra Biotechnology Co., Ltd.

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GW1516 Cardarine GW501516
Product Name:
GW1516 Cardarine GW501516
No. :
317318-70-0
:
:

Product Description:

Name:2-(4-((2-(4-(Trifluoromethyl)phenyl)-5-methylthiazol-4-yl)methylthio)-2-methylphenoxy)acetic acid
CAS:317318-70-0
MF:C21H18F3NO3S2
MW:453.5
EINECS:1592732-453-0 

GW501516 (also known as GW-501,516, GW1516, GSK-516, Cardarine, and on the black market as Endurobol[1]) is a PPARδ receptor agonist that was invented in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s. It entered into clinical development as a drug candidate for metabolic and cardiovascular diseases, but was abandoned in 2007 because animal testing showed that the drug caused cancer to develop rapidly in several organs.

In 2007, research was published showing that high doses of GW501516 given to mice dramatically improved their physical performance; the work was widely discussed in popular media, and led to a black market for the drug candidate and to its abuse by athletes as a doping agent. The World Anti-Doping Agency (WADA) developed a test for GW501516 and other related chemicals and added them to the prohibited list in 2009; it has issued additional warnings to athletes that GW501516 is not safe.