Synonyms: TIANEPTINE;7-[(3-chloro-6,11-dihydro-6-methyldibenzo[c,f][1,2]thiazepin-11-yl)-amino]heptanoic acid s,s-dioxide;7-[(3-CHLORO-6,11-DIHYDRO-6-METHYL-DIBENZO[C,F][1,2]THIAZEPINE-11-YL)AMINO]HEPTANOIC ACID S,S DIOXIDE;Tianeptineacid;COAXIL;7-[(3-Chloro-6，11-dihydro-6-methyldibenzo[c，f][1，2]thiazepin-11-y1)amino]heptanoic acid S，S-dioxide;30123-17-2 (Mono-hydrochloride salt);Brn 1232295
TIANEPTINE: WHAT IS TIANEPTINE?
There are a number of drugs being tested and already on the marker that qualifies as nootropics, which are presented as “Smart Drugs”. Smart Drugs are believed to be low-risk and work to improve, enhance, or repair damage done to the brain via injury or disease. Most of the nootropics commonly discussed fall under the heading of Racetam, yet there are many that do not. Tianeptine is a nootropic, but it is classified as an antidepressant selective serotonin re-uptake enhancer (SSRE). Tianeptine is generally prescribed in doses broken up into individual doses of approximately 12 mg each, in the treatment of severe depression, anxiety disorders, bipolar disorder, and other “adjustment disorders”. In clinical trials, it has been determined that Tianeptine is as efficient as more common antidepressants, like amitriptyline and clomipramine. In addition, their effectiveness seems to require a smaller dose than the traditional antidepressants, as well (Wagstaff & et. al, 2001).
HOW DOES TIANEPTINE WORK?
What makes Tianeptine so effective is that it reduces stress on the brain, both physical and mental. Tianeptine causes stress-induced alterations morphology and synaptic plasticity. As it alleviates stress, it also improved learning, brain cognition and memory, two things often diminished by serious depressive conditions. (Zoldaz & et. al, 2010). Like many drugs, there are still studies and concerns that the efficiency and effectiveness of Tianeptine as a whole is difficult to ascertain. After all, Tianeptine, like many drugs, can have a vastly distinct effect on some people and entirely different one on others. More studies are needed to determine if there is a universal dose or regiment that can produce absolute results.
TIANEPTINE SIDE EFFECTS
Unlike many antidepressants,Tianeptine has few negative side effects; Tianeptine is showing promise as an alternative to traditional antidepressants and their addictive nature and long-list of side effects.While the majority of antidepressant users do not abuse or misuse the medication, they are prescribed, that does not speak to the rest of the public. Antidepressants are a very popular and dangerous recreational activity. For people who do not need them, the taking of such drugs can come with many negative side effects and potential addictive properties. Tianeptine may be a much safer alternative to many of the antidepressants on the market today. The listing of side effects that are associated with are minor and tolerable, they include drowsiness, dry-mouth, insomnia, dizziness, constipation, bouts of low blood pressure, and some patients describe unusually vivid dreams.
BENEFITS AND EFFECTS OF TIANEPTINE
This multitasking drug has a great deal of potential in medicine, therapeutic psychological and counseling goals, and provides a potential enhancement to brain function. Finding way to improve the mental state of those suffering from debilitating disease and emotional conditions that are both effective, efficient, and has a limited amount of serious side effects is worthwhile. Granted, it is necessary that experts and researchers continue their studies to determine if there are any deleterious effects or unforeseen consequences that have yet to be discovered. However, as with all drugs, regardless of the side effects, should not be taken outside of a professional’s care or for recreational purposes. Even so, it would appear that the future of Tianeptine is to be a positive one, and with further research and study may become one of the mainstay medications prescribed to address depression in more patients who require them.