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Nefiracetam CAS 77191-36-7
Product Name:
Nefiracetam CAS 77191-36-7
No. :

Product Description:

Product Name: Nefiracetam
Synonyms: n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamide;NEFIRACETAM;2-oxo-1-pyrrolidinylaceticacid,2,6-dimethylanilide;dm9384;dmppa;n-(2,6-dimethylphenyl)-2-oxo-1-pyrrolidineacetamid;DM-9384, (2-(2-Oxopyrrolidin-1-yl)-N-(2,6-dimethylphenyl)-acetamide);DMMPA
CAS: 77191-36-7
MF: C14H18N2O2
MW: 246.3 

Mechanism Of Action

nefiracetam experienceNefiracetam works in a few different mechanisms of action, some of which comport closely with other Racetams and others which you may not be familiar with from using Aniracetam or Piracetam.

The first of these is through prolonging the opening of calcium channels. By taking Nefiracetam, you can enhance the signaling of a receptor independent of the synapse basically resulting in more stimulation to the brain and making it more likely that any single neuron will fire.

When you keep the calcium channels open for a longer period of time, you can amplify the message sent by any excitatory neurotransmitter which may produce higher levels of memory formation and more communication between different areas of the brain.

The second method of action associated with Nefiracetam involves the potentiation of nicotinic Acetylcholine receptors. This action has a number of different effects including the release of GABA and Glutamate, which are two of the most powerful neurotransmitters within the brain.

GABA is actually the main inhibitory chemical and helps to calm the brain down, making it easier to relieve stress, anxiety, depression, and just simply relax.

Glutamate and Acetylcholine are both also believed to play a crucial role in the development of memories, expanding learning capacity, and a wide range of additional cognitive processes and functions.

These two neurochemicals are also highly connected to the idea of synaptic plasticity and can promote the formation of new neurons and pathways in your brain.

Nefiracetam Dosage Suggestion

Supplementation of nefiracetam appears to be in the 150-450mg range over the course of a day (usually divided into three even doses). Animal studies using acute doses tend to note most benefits in the 3-10mg/kg range, and this correlates to a human dose of 0.48-1.6mg/kg (for a 150lb person, 33-110mg) which is similar to the aforementioned human doses.

Although single doses of nefiracetam do not appear to promote cognition, it is able to affect the brain within 30-60 minutes following oral ingestion. It is not certain whether nefiracetam needs to be taken prior to cognitive training.